Ivabradine is indicated in chronic heart failure with systolic dysfunction in patients with:

  • NYHA II to IV class

  • sinus rhythm

  • heart rate ≥ 75 bpm

– in combination with standard therapy including β-blocker therapy
– or when β-blocker therapy is contraindicated or not tolerated.

Ivabradine is indicated in symptomatic treatment of chronic stable angina pectoris in coronary artery disease adults with normal sinus rhythm and heart rate ≥70 bpm. Ivabradine is indicated:

– in adults unable to tolerate or with a contraindication to the use of β-blockers ,
– or in combination with β-blockers in patients inadequately controlled with an optimal β-blocker dose.1


1. Procoralan Summary of Product Characteristics. (EUROPE – latest update of January 2015)